Smith modeled for huge names in the fashion industry among which Guess, H&M, Heatherette and Lane Bryant.

16 years after her death, the name of Anna Nicole Smith still stands for fame and controversy. She was a model, an actress, and a television personality who first gained popularity when she won the title of 1993 Playmate of the Year after posing for Playboy magazine.

“I love the paparazzi,” she once told the Washington Post.

“They take pictures, and I just smile away. I’ve always liked the attention. I didn’t get very much growing up, and I always wanted to be, you know, noticed.”

Anna Nicole Smith in 1990 (Photo by Barry King/WireImage)

Sadly, the life of glamour took its toll. Smith married petroleum tycoon J. Howard Marshall who was 63 years her senior. This relationship wasn’t just controversial, but a high-profile one and many believe it marked the start of Smith’s downfall. Six months after tying the knot, then 90-year-old Marshal died.

Following his passing, Smith and Marshal’s family got involved in a long and controversial legal battle over his fortune and assets. The case ultimately went as high as the US Supreme Court in 2006.

In 2007, a tragedy struck beautiful Smith died of overdose in 2007, just a few months after she gave birth to her baby daughter Dannielynn. After her death, several men claimed to be the baby’s dad and after paternity tests were ordered, Larry Birkhead got paternity rights.

Today, Dannielynn is all grown up and resembles both her mom and her dad. In fact, she got the best of both and is a real beauty.

Larry takes great care of his daughter and shares adorable photos of the fun time they spend together. They live in Kentucky and Larry makes sure his daughter’s life is as normal as possible. She attends a public school and has a lot of friends.

A photograph of Anna Nicole Smith and J. Howard Marshall II sits next to Marshall’s casket. (Photo by Greg Smith/CORBIS/Corbis via Getty Images)

Speaking of her likes and dislikes and what makes her happy, Larry says Dannielynn wants to follow into her late mom’s footsteps when it comes to acting.

The girl once said, “It’s really cool to like, act as a character and not yourself. It’s like portraying a new person. It’s fun.” She and her dad have appeared on several shows such as ‘Life after Anna’, ‘Wife Swap‘, and ‘The Millionaire Matchmaker.’

Dannielynn wants to try herself as a YouTuber, but her dad thinks she’s way too young to be doing something like that. He wants her to stay out of the spotlight and enjoy her teen years the way her friends do. Speaking to US Weekly, Larry said, “If it’s something you want to do when you get older, you can, but right now let’s sell some Girl Scout cookies.”

© Facebook/DanielynnHope

Some years ago, an unnamed source told National Enquirer, “Anna Nicole was seduced by the showbiz lifestyle, and Larry wants to make sure Dannielynn doesn’t end up like her. “[Anna Nicole was] chasing stardom and surrounded by greedy hangers-on.”

However, Larry does his best to keep the memory of Smith alive. Last year, Dannielynn paid tribute to her mom by wearing her heat from her appearance at the Kentucky Derby in 2004 and a pink dress. The resemblance with her mom is there, although as she grows older, Dannielynn seems to be taking more after her dad.

Speaking of her character, Larry told Fox News, “She’s fun and fearless like her mom was. She’s a good kid. I’m just happy that I’ve been able to spend all the time I have been able to have with her.”

Getty Images – Stephen J. Cohen 

At the Barnstable Brown Gala that took place ahead of the Derby, the now-17-year-old wore a blouse with photographs of her mom. Larry wore a tie featuring the same images.

“She’s showing off her fashion sense but at the same time paying tribute to her mom,” Larry said. He added that he and his daughter had decided to pay tribute to Anna Nicole Smith because it marked the 20th anniversary of the day he had met the model back in 2003. At the time, he was a photographer covering the event.

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The late model’s clothes are in Larry’s possession so Dannielynn often goes through them.

“And everything she has of her mom’s is cataloged in storage, with photos of the event where she wore it,” Larry revealed.

“So someday, she can give them to her kids if she wants to.”

We hope Dannielynn will fulfill all her dreams.

We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth

The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.

A dental breakthrough

While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.

A bit of science

The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.

As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.

On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.

BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.

“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.

The first results

Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.

“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.

Fully regrown frontal teeth in ferrets

The next steps

Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontiaa genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.

Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.

“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”

So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.

Preview photo credit KyotoU_News / Twitter

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