Joining in the trend of wearing sheer dresses, Demi Moore turned heads at a recent fashion event. The actress paired the dress with black underwear and looked younger than ever.
Demi’s youthful bold look.
The 61-year-old actress wore a sequin-covered gown with black underwear and minimal makeup. For Dolce & Gabbana’s 40th anniversary party, Demi Moore chose a long, transparent black dress that was adorned with shiny decorations from top to bottom. The dress had a simple shape, full sleeves, and a modest neckline.
Moore looked radiant, with the dress’s sequins shimmering in the light. She wore this over basic black undergarments and added a pair of simple black heels with straps. Choosing to let her dress be the center of attention, Moore didn’t wear any jewelry. Her makeup was light and natural, highlighting her features with soft-pink lipstick and bold mascara.
Her appearance gained praise.
Her beautiful dark hair was the perfect complement to her outfit, worn straight and parted down the middle, falling gracefully to her waist. Fans poured in praise for Demi’s youthful, radiant look. “You look so amazing, and I love how you haven’t needed around with your face like lots of others,” commented one. “She looks unreal for her age. BRAVO,” added another.
Demi previously denied having surgery.
Demi Moore addressed the speculation about her undergoing plastic surgery. She clarified in an old interview, “I have had something done but it’s not on my face.” She left open the possibility of future procedures by adding, “Maybe one day I’ll go under the knife.” Moore expressed her frustration with the ongoing rumors, stating, “It just irritates me that people are constantly saying how much I’ve spent on plastic surgery.”
Before Moore’s appearance, Katy Perry also embraced the see-through fashion trend. Check out her photos here.
Preview photo credit STEPHANE DE SAKUTIN/AFP/East News, demimoore / Instagram
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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