Following Oprah Winfrey’s hospitalization earlier this week, her friend Gayle King is finally discussing what transpired. Oprah did not make her normal appearance to present her book pick during the most recent broadcast of Oprah’s Book Club on CBS.
Rather, Gayle King gave author David Wroblewski, who was present in the studio, an explanation of Oprah’s absence. “I’m glad you’re here, and I apologize that Oprah can’t,” Gayle remarked. She declared yesterday that she would hold a rally. She was sick from head to toe with a severe case of stomach flu.
Nervously, Gayle King apologized, hoping that sharing that detail wouldn’t hurt Oprah. She wanted everyone to know how much Oprah valued being present, even if she was ill and was unable to do so. Gayle gave everyone the assurance that they would make up for her loss.
Oprah’s Book Club selected the author in 2008, and Gayle, Nate Burleson, and Tony Dokoupil had a conversation with her during the show.
Following Gayle’s mention of Oprah’s health, Oprah’s representative offered an explanation on Oprah Daily’s Instagram, stating that Oprah was unable to appear on CBS Mornings to reveal her next book club selection. It was said that Oprah was suffering from a stomach ailment, and Gayle, who is a close friend, took over to give the news. Following her doctor’s advise and receiving an IV for dehydration, Oprah recovered. Everyone hoped she recovered quickly.
Oprah and her crew released an official statement along with the caption. “Ms. Winfrey is recuperating following a stomach virus and receiving an IV for dehydration as prescribed by her physician,” the statement read. She is getting more rest and improving every day.
In a video chat with Gayle King later on Tuesday, Oprah said that she visited the emergency room for fluids rather than the hospital.
“I was at the urgent care facility. I was quite dehydrated,” declared Oprah. “My mouth felt dry, and I was unable to drink enough water to stay hydrated, so that’s why I went to the emergency room,” she continued.
Oprah Winfrey responded, “I’m not completely better yet, but I’m getting there,” when questioned about her health. She clarified that her recent illness prevented her from flying, which is why she was unable to appear on CBS Mornings.
Oprah went to the hospital for an IV drip because she became extremely dehydrated due to a gastrointestinal bug, as Gayle King stated in her post.
“I thought I clarified that, but then I noticed headlines stating that Oprah was admitted to the hospital. (She wasn’t.) And many people called to check on Oprah,” King remarked. She is, in fact, fine! And let’s hear her say it directly.
The good news is that Oprah is back to normal! Around the world, the 70-year-old is adored. To calm any Oprah fans who may have been concerned about her, share this!
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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